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Inosine

Inosine

Inosine is a nucleoside, one of the basic compounds comprising cells. It is a precursor to adenosine, an important energy molecule, and plays many supportive roles in the body in Rizer XL's™ exclusive formula.

According to our research, Inosine has been investigated for exercise-boosting (ergogenic) effects.

It is a natural substance that helps increase the body's ability to carry oxygen, without affecting its uptake in the lungs, so it can work harder and stronger. When physical exertion is reached Inosine is converted into nutrients used by the body.

Sexual activity is an energy consuming activity that not everyone can maintain for long periods. Rizer XL™ is the only male enhancement supplement committed to providing the stamina and endurance necessary for intense sexual encounters guaranteed to satisfy any partner's physical needs. Inosine starts by first becoming an excellent precursor to energy metabolizing agents and also with enhancing the user's physical appearance.

Inosine is effective in:

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Scientific Literature and References

1. Hamann M, Pierra C, Sommadossi JP, Musiu C, Vargiu L, Liuzzi M, Storer R, Gosselin G "Synthesis and antiviral evaluation of thieno[3,4-d]pyrimidine C-nucleoside analogues of 2',3'-dideoxy- and 2',3'-dideoxy-2',3'-didehydro-adenosine and –inosine" Bioorg Med Chem. 2009 Mar 15;17(6):2321-6. Epub 2009 Feb 14

2. Kan Uchiyama1 , Makoto Nakamura1, Takahiro Kubota2, Tateki Yamane1, Kiyotaka Fujise1 and Hisao Tajiri1 "Thiopurine S -methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment." Journal of Gastroenterology Volume 44, Number 3 / March, 2009

3. Li S, Juan YS, Kogan BA, Mannikarottu A, Leggett R, Schuler C, Levin RM "Effects of inosine on response to in vitro hypoxia in absence of substrate on bladder dysfunction in adult rats" Urology. 2009 Mar;73(3):661-4. Epub 2008 Dec 21

4. McNaughton L, Dalton B, Tarr J (1999). "Inosine supplementation has no effect on aerobic or anaerobic cycling performance". International journal of sport nutrition 9 (4): 333–44

5. Achille C. Pessina2 and Graham J. MacDonald1 "The effect of uridine and inosine on capillary permeability in the rat Volume 10, Number 3 / July, 1980
Seaman C, Moritz J, Falkenstein E, Van Dyke K, Casotti G, Klandorf H. Inosine ameliorates the effects of hemin-induced oxidative stress in broilers Comp" Biochem Physiol A Mol Integr Physiol. 2008 Aug 22

6. Zlatina Naydenova, Jennifer B. Rose, and Imogen R. Coe "Inosine and equilibrative nucleoside transporter 2 contribute to hypoxic preconditioning in the murine cardiomyocyte HL-1 cell line" Am J Physiol Heart Circ Physiol 294: H2687-H2692, 2008. First published April 18, 2008

7. Maxim Pimkin and George D. Markham "The CBS subdomain of inosine 5'-monophosphate dehydrogenase regulates purine nucleotide turnover." Molecular Microbiology
Volume 68 Issue 2, Pages 342 – 359 Published Online: 28 Feb 2008

8. Starling RD, Trappe TA, Short KR, et al. "Effect of inosine supplementation on aerobic and anaerobic cycling performance." Med Sci Sports Ex 1996;28:1193–8.

 
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